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2021-2024

  1. Sang-Hyeon Hann, Seon-Yong Kim, Ye Lynne Kim, Young-Woo Jo, Jong-Seol Kang, Hyerim Park, Se-Young Choi, Young-Yun Kong. Depletion of SMN protein in mesenchymal progenitors impairs the development of bone and neuromuscular junction in spinal muscular atrophy. eLife. 2024 Feb;12:RP92731. doi: https://doi.org/10.7554/eLife.92731.3

  2. Oh E, Lee J, Cho S, Kim SW, Won K, Shin WS, Gwak SH, Ha J, Jeon SY, Park JH, Song IS, Thoudam T, Lee IK, Kim S, Choi SY, Kim KT. Gossypetin Prevents the Progression of Nonalcoholic Steatohepatitis by Regulating Oxidative Stress and AMP-Activated Protein Kinase. Mol Pharmacol. 2023 Nov;104(5):214-229. doi: 10.1124/molpharm.123.000675. 

  3. Noh K, Cho WH, Lee BH, Kim DW, Kim YS, Park K, Hwang M, Barcelon E, Cho YK, Lee CJ, Yoon BE, Choi SY, Park HY, Jun SB, Lee SJ. Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance. Nat Neurosci. 2023 Sep;26(9):1541-1554. doi: 10.1038/s41593-023-01406-4.

  4. Choi Y, Nam YH, Jeong S, Lee HY, Choi SY, Park S, Jung SC. Biochemical and functional characterization of skeletal muscle cells differentiated from tonsil-derived mesenchymal stem cells. Muscle Nerve. 2023 Aug;68(2):219-229. doi: 10.1002/mus.27847.

  5. Lee J, Kim S, Lee B, Kim YB, Kim KH, Chung G, Lee SJ, Lee S, Sun W, Park HK, Choi SY. Major depression-related factor NEGR1 controls salivary secretion in mouse submandibular glands. iScience. 2023 Apr 26;26(5):106773. doi: 10.1016/j.isci.2023.106773.

  6. Lee JH, Shin H, Shaker MR, Kim HJ, Park SH, Kim JH, Lee N, Kang M, Cho S, Kwak TH, Kim JW, Song MR, Kwon SH, Han DW, Lee S, Choi SY, Rhyu IJ, Kim H, Geum D, Cho IJ, Sun W. Production of human spinal-cord organoids recapitulating neural-tube morphogenesis. Nat Biomed Eng. 2022 Apr;6(4):435-448. doi: 10.1038/s41551-022-00868-4.

  7. Lie E, Yeo Y, Lee EJ, Shin W, Kim K, Han KA, Yang E, Choi TY, Bae M, Lee S, Um SM, Choi SY, Kim H, Ko J, Kim E. SALM4 negatively regulates NMDA receptor function and fear memory consolidation. Commun Biol. 2021 Sep 29;4(1):1138. doi: 10.1038/s42003-021-02656-3.

  8. Kim SW, Woo HJ, Kim EH, Kim HS, Suh HN, Kim SH, Song JJ, Wulansari N, Kang M, Choi SY, Choi SJ, Jang WH, Lee J, Kim KH, Lee W, Kim SH, Yang J, Kyung J, Lee HS, Park SM, Chang MY, Lee SH. Neural stem cells derived from human midbrain organoids as a stable source for treating Parkinson's disease: Midbrain organoid-NSCs (Og-NSC) as a stable source for PD treatment. Prog Neurobiol. 2021 Sep;204:102086. doi: 10.1016/j.pneurobio.2021.102086.

  9. Lee J, Kim YJ, Choi LM, Lee K, Park HK, Choi SY. Muscarinic Receptors and BK Channels Are Affected by Lipid Raft Disruption of Salivary Gland Cells. Int J Mol Sci. 2021 Apr 30;22(9):4780. doi: 10.3390/ijms22094780.

  10. Zhang Y, Kang Hyae R, Lee SH, Kim Y, Ma R, Jin C, Lim JE, Kim S, Kang Y, Kang H, Kim SY, Kwon SK, Choi SY, Han K. Enhanced Prefrontal Neuronal Activity and Social Dominance Behavior in Postnatal Forebrain Excitatory Neuron-Specific Cyfip2 Knock-Out Mice. Front Mol Neurosci. 2020 Oct 29;13:574947. doi: 10.3389/fnmol.2020.574947.

  11. Um JW, Han KA, Choi SY, Ko J. Protocol for Quantitative Analysis of Synaptic Vesicle Clustering in Axons of Cultured Neurons. STAR Protoc. 2020 Aug 21;1(2):100095. doi: 10.1016/j.xpro.2020.100095.

  12. Han KA, Kim YJ, Yoon TH, Kim H, Bae S, Um JW, Choi SY, Ko J. LAR-RPTPs Directly Interact with Neurexins to Coordinate Bidirectional Assembly of Molecular Machineries. J Neurosci. 2020 Oct 28;40(44):8438-8462. doi: 10.1523/JNEUROSCI.1091-20.2020.

  13. Kim GH, Zhang Y, Kang HR, Lee SH, Shin J, Lee CH, Kang H, Ma R, Jin C, Kim Y, Kim SY, Kwon SK, Choi SY, Lee KJ, Han K. Altered presynaptic function and number of mitochondria in the medial prefrontal cortex of adult Cyfip2 heterozygous mice. Mol Brain. 2020 Sep 11;13(1):123. doi: 10.1186/s13041-020-00668-4.

  14. Lee SH, Zhang Y, Park J, Kim B, Kim Y, Lee SH, Kim GH, Huh YH, Lee B, Kim Y, Lee Y, Kim JY, Kang H, Choi SY, Jang S, Li Y, Kim S, Jin C, Pang K, Kim E, Lee Y, Kim H, Kim E, Choi JH, Kim J, Lee KJ, Choi SY, Han K. Haploinsufficiency of Cyfip2 Causes Lithium-Responsive Prefrontal Dysfunction. Ann Neurol. 2020 Sep;88(3):526-543. doi: 10.1002/ana.25827.

  15. Han KA, Lee HY, Lim D, Shin J, Yoon TH, Liu X, Um JW, Choi SY, Ko J. Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses. Mol Brain. 2020 Jun 17;13(1):94. doi: 10.1186/s13041-020-00629-x.

  16. Han KA, Lee HY, Lim D, Shin J, Yoon TH, Lee C, Rhee JS, Liu X, Um JW, Choi SY, Ko J. PTPσ Controls Presynaptic Organization of Neurotransmitter Release Machinery at Excitatory Synapses. iScience. 2020 Jun 26;23(6):101203. doi: 10.1016/j.isci.2020.101203. 

  17. Kim H, Kim D, Kim J, Lee HY, Park D, Kang H, Matsuda K, Sterky FH, Yuzaki M, Kim JY, Choi SY, Ko J, Um JW. Calsyntenin-3 interacts with both α- and β-neurexins in the regulation of excitatory synaptic innervation in specific Schaffer collateral pathways. J Biol Chem. 2020 Jul 3;295(27):9244-9262. doi: 10.1074/jbc.RA120.013077. 

  18. Lee Y, Han NE, Kim W, Kim JG, Lee IB, Choi SJ, Chun H, Seo M, Lee CJ, Koh HY, Kim JH, Baik JH, Bear MF, Choi SY, Yoon BJ. Dynamic Changes in the Bridging Collaterals of the Basal Ganglia Circuitry Control Stress-Related Behaviors in Mice. Mol Cells. 2020 Apr 30;43(4):360-372. doi: 10.14348/molcells.2019.0279. 

2016-2020

  1. Lee J, Kim YJ, Choi LM, Lee K, Park HK, Choi SY. Muscarinic Receptors and BK Channels Are Affected by Lipid Raft Disruption of Salivary Gland Cells. Int J Mol Sci. 2021 Apr 30;22(9):4780. doi: 10.3390/ijms22094780.

  2. Zhang Y, Kang Hyae R, Lee SH, Kim Y, Ma R, Jin C, Lim JE, Kim S, Kang Y, Kang H, Kim SY, Kwon SK, Choi SY, Han K. Enhanced Prefrontal Neuronal Activity and Social Dominance Behavior in Postnatal Forebrain Excitatory Neuron-Specific Cyfip2 Knock-Out Mice. Front Mol Neurosci. 2020 Oct 29;13:574947. doi: 10.3389/fnmol.2020.574947.

  3. Um JW, Han KA, Choi SY, Ko J. Protocol for Quantitative Analysis of Synaptic Vesicle Clustering in Axons of Cultured Neurons. STAR Protoc. 2020 Aug 21;1(2):100095. doi: 10.1016/j.xpro.2020.100095.

  4. Han KA, Kim YJ, Yoon TH, Kim H, Bae S, Um JW, Choi SY, Ko J. LAR-RPTPs Directly Interact with Neurexins to Coordinate Bidirectional Assembly of Molecular Machineries. J Neurosci. 2020 Oct 28;40(44):8438-8462. doi: 10.1523/JNEUROSCI.1091-20.2020.

  5. Kim GH, Zhang Y, Kang HR, Lee SH, Shin J, Lee CH, Kang H, Ma R, Jin C, Kim Y, Kim SY, Kwon SK, Choi SY, Lee KJ, Han K. Altered presynaptic function and number of mitochondria in the medial prefrontal cortex of adult Cyfip2 heterozygous mice. Mol Brain. 2020 Sep 11;13(1):123. doi: 10.1186/s13041-020-00668-4.

  6. Lee SH, Zhang Y, Park J, Kim B, Kim Y, Lee SH, Kim GH, Huh YH, Lee B, Kim Y, Lee Y, Kim JY, Kang H, Choi SY, Jang S, Li Y, Kim S, Jin C, Pang K, Kim E, Lee Y, Kim H, Kim E, Choi JH, Kim J, Lee KJ, Choi SY, Han K. Haploinsufficiency of Cyfip2 Causes Lithium-Responsive Prefrontal Dysfunction. Ann Neurol. 2020 Sep;88(3):526-543. doi: 10.1002/ana.25827.

  7. Han KA, Lee HY, Lim D, Shin J, Yoon TH, Liu X, Um JW, Choi SY, Ko J. Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses. Mol Brain. 2020 Jun 17;13(1):94. doi: 10.1186/s13041-020-00629-x.

  8. Han KA, Lee HY, Lim D, Shin J, Yoon TH, Lee C, Rhee JS, Liu X, Um JW, Choi SY, Ko J. PTPσ Controls Presynaptic Organization of Neurotransmitter Release Machinery at Excitatory Synapses. iScience. 2020 Jun 26;23(6):101203. doi: 10.1016/j.isci.2020.101203. 

  9. Kim H, Kim D, Kim J, Lee HY, Park D, Kang H, Matsuda K, Sterky FH, Yuzaki M, Kim JY, Choi SY, Ko J, Um JW. Calsyntenin-3 interacts with both α- and β-neurexins in the regulation of excitatory synaptic innervation in specific Schaffer collateral pathways. J Biol Chem. 2020 Jul 3;295(27):9244-9262. doi: 10.1074/jbc.RA120.013077. 

  10. Lee Y, Han NE, Kim W, Kim JG, Lee IB, Choi SJ, Chun H, Seo M, Lee CJ, Koh HY, Kim JH, Baik JH, Bear MF, Choi SY, Yoon BJ. Dynamic Changes in the Bridging Collaterals of the Basal Ganglia Circuitry Control Stress-Related Behaviors in Mice. Mol Cells. 2020 Apr 30;43(4):360-372. doi: 10.14348/molcells.2019.0279. 

  11. Kim YJ, Jo Y, Lee YH, Park K, Park HK, Choi SY. Zn2+ stimulates salivary secretions via metabotropic zinc receptor ZnR/GPR39 in human salivary gland cells. Sci Rep. 2019 Nov 27;9(1):17648. doi: 10.1038/s41598-019-54173-3. 

  12. Nam MH, Han KS, Lee J, Won W, Koh W, Bae JY, Woo J, Kim J, Kwong E, Choi TY, Chun H, Lee SE, Kim SB, Park KD, Choi SY, Bae YC, Lee CJ. Activation of Astrocytic μ-Opioid Receptor Causes Conditioned Place Preference. Cell Rep. 2019 Jul 30;28(5):1154-1166.e5. doi: 10.1016/j.celrep.2019.06.071. 

  13. Lee J, Lee S, Ryu YJ, Lee D, Kim S, Seo JY, Oh E, Paek SH, Kim SU, Ha CM, Choi SY, Kim KT. Vaccinia-related kinase 2 plays a critical role in microglia-mediated synapse elimination during neurodevelopment. Glia. 2019 Sep;67(9):1667-1679. doi: 10.1002/glia.23638.

  14. Noh K, Lee H, Choi TY, Joo Y, Kim SJ, Kim H, Kim JY, Jahng JW, Lee S, Choi SY, Lee SJ. Negr1 controls adult hippocampal neurogenesis and affective behaviors. Mol Psychiatry. 2019 Aug;24(8):1189-1205. doi: 10.1038/s41380-018-0347-3. 

  15. Choi TY, Lee SH, Kim SJ, Jo Y, Park CS, Choi SY. BK channel blocker paxilline attenuates thalidomide-caused synaptic and cognitive dysfunctions in mice. Sci Rep. 2018 Dec 5;8(1):17653. doi: 10.1038/s41598-018-36367-3.

  16. Min H, Cho WH, Lee H, Choi B, Kim YJ, Lee HK, Joo Y, Jung SJ, Choi SY, Lee S, Lee SJ. Association of TRPV1 and TLR4 through the TIR domain potentiates TRPV1 activity by blocking activation-induced desensitization. Mol Pain. 2018 Jan-Dec;14:1744806918812636. doi: 10.1177/1744806918812636. 

  17. Park SW, Kim J, Kang M, Lee W, Park BS, Kim H, Choi SY, Yang S, Ahn JH, Yang S. Epidural Electrotherapy for Epilepsy. Small. 2018 Jul;14(30):e1801732. doi: 10.1002/smll.201801732. 

  18. Bridi MCD, de Pasquale R, Lantz CL, Gu Y, Borrell A, Choi SY, He K, Tran T, Hong SZ, Dykman A, Lee HK, Quinlan EM, Kirkwood A. Two distinct mechanisms for experience-dependent homeostasis. Nat Neurosci. 2018 Jun;21(6):843-850. doi: 10.1038/s41593-018-0150-0. 

  19. Choi SY. Synaptic and circuit development of the primary sensory cortex. Exp Mol Med. 2018 Apr 9;50(4):1-9. doi: 10.1038/s12276-018-0029-x. 

  20. Choi TY, Lee SH, Kim YJ, Bae JR, Lee KM, Jo Y, Kim SJ, Lee AR, Choi S, Choi LM, Bang S, Song MR, Chung J, Lee KJ, Kim SH, Park CS, Choi SY. Cereblon Maintains Synaptic and Cognitive Function by Regulating BK Channel. J Neurosci. 2018 Apr 4;38(14):3571-3583. doi: 10.1523/JNEUROSCI.2081-17.2018. 

  21. Park SH, Kim YJ, Park JC, Han JS, Choi SY. Intranasal Oxytocin following Uncontrollable Stress Blocks Impairments in Hippocampal Plasticity and Recognition Memory in Stressed Rats. Int J Neuropsychopharmacol. 2017 Oct 1;20(10):861-866. doi: 10.1093/ijnp/pyx061.

  22. Kang MS, Choi TY, Ryu HG, Lee D, Lee SH, Choi SY, Kim KT. Autism-like behavior caused by deletion of vaccinia-related kinase 3 is improved by TrkB stimulation. J Exp Med. 2017 Oct 2;214(10):2947-2966. doi: 10.1084/jem.20160974. 

  23. Lee K, Kim YJ, Cho YY, Chung S, Jo SH, Choi SY. Polychlorinated biphenyl 19 blocks the most common form of store-operated Ca2+ entry through Orai. Naunyn Schmiedebergs Arch Pharmacol. 2017 Dec;390(12):1221-1228. doi: 10.1007/s00210-017-1420-1. 

  24. Kim D, Chung S, Lee SH, Choi SY, Kim SM, Koo J, Lee JH, Jahng JW. Decreased hippocampal brain-derived neurotrophic factor and impaired cognitive function by hypoglossal nerve transection in rats. J Cell Mol Med. 2017 Dec;21(12):3752-3760. doi: 10.1111/jcmm.13284.

  25. Roh JD, Choi SY, Cho YS, Choi TY, Park JS, Cutforth T, Chung W, Park H, Lee D, Kim MH, Lee Y, Mo S, Rhee JS, Kim H, Ko J, Choi SY, Bae YC, Shen K, Kim E, Han K. Increased Excitatory Synaptic Transmission of Dentate Granule Neurons in Mice Lacking PSD-95-Interacting Adhesion Molecule Neph2/Kirrel3 during the Early Postnatal Period. Front Mol Neurosci. 2017 Mar 22;10:81. doi: 10.3389/fnmol.2017.00081. 

  26. Lee K, Kim YJ, Choi LM, Choi S, Nam H, Ko HY, Chung G, Lee JH, Jo SH, Lee G, Choi SY, Park K. Human salivary gland cells express bradykinin receptors that modulate the expression of proinflammatory cytokines. Eur J Oral Sci. 2017 Feb;125(1):18-27. doi: 10.1111/eos.12324. 

  27. Shin YH, Lee SW, Kim M, Choi SY, Cong X, Yu GY, Park K. Epigenetic regulation of CFTR in salivary gland. Biochem Biophys Res Commun. 2016 Dec 2;481(1-2):31-37. doi: 10.1016/j.bbrc.2016.11.023. 

  28. Lee SH, Kim YJ, Choi SY. BMP signaling modulates the probability of neurotransmitter release and readily releasable pools in Drosophila neuromuscular junction synapses. Biochem Biophys Res Commun. 2016 Oct 21;479(3):440-446. doi: 10.1016/j.bbrc.2016.09.072.

  29. Lie E, Ko JS, Choi SY, Roh JD, Cho YS, Noh R, Kim D, Li Y, Kang H, Choi TY, Nam J, Mah W, Lee D, Lee SG, Kim HM, Kim H, Choi SY, Um JW, Kang MG, Bae YC, Ko J, Kim E. SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. Nat Commun. 2016 Aug 2;7:12328. doi: 10.1038/ncomms12328. 

  30. Choi SY, Lee K, Park Y, Lee SH, Jo SH, Chung S, Kim KT. Non-Dioxin-Like Polychlorinated Biphenyls Inhibit G-Protein Coupled Receptor-Mediated Ca2+ Signaling by Blocking Store-Operated Ca2+ Entry. PLoS One. 2016 Mar 10;11(3):e0150921. doi: 10.1371/journal.pone.0150921. 

  31. Um JW, Choi TY, Kang H, Cho YS, Choii G, Uvarov P, Park D, Jeong D, Jeon S, Lee D, Kim H, Lee SH, Bae YC, Choi SY, Airaksinen MS, Ko J. LRRTM3 Regulates Excitatory Synapse Development through Alternative Splicing and Neurexin Binding. Cell Rep. 2016 Feb 2;14(4):808-822. doi: 10.1016/j.celrep.2015.12.081. 

  32. Kim Y, Choi H, Lee W, Park H, Kam TI, Hong SH, Nah J, Jung S, Shin B, Lee H, Choi TY, Choo H, Kim KK, Choi SY, Kayed R, Jung YK. Caspase-cleaved tau exhibits rapid memory impairment associated with tau oligomers in a transgenic mouse model. Neurobiol Dis. 2016 Mar;87:19-28. doi: 10.1016/j.nbd.2015.12.006. 

2011-2015

  1. Lee SY, Park SH, Chung C, Kim J, Choi SY*, Han JS*. Oxytocin protects hippocampal memory and plasticity from uncontrollable stress. Sci Rep. 2015 Dec 21;5:18540. doi: 10.1038/srep18540.

  2. Shin YH, Kim M, Kim N, Choi SK, Namkoong E, Choi SY, Lee JH, Cha S, Park K. Epigenetic alteration of the purinergic type 7 receptor in salivary epithelial cells. Biochem Biophys Res Commun. 2015 Oct 30;466(4):704-10. doi: 10.1016/j.bbrc.2015.09.095.

  3. Li Y, Zhang P, Choi TY, Park SK, Park H, Lee EJ, Lee D, Roh D, Mah W, Kim R, Kwon H, Bae YC, Choi SY, Craig AM, Kim E. Splicing-dependent transsynaptic interactions between SALM3 and LARRPTPs regulate excitatory synapse development and locomotion behavior. Cell Rep. 2015 Sep 8;12(10):1618-30. doi: 10.1016/j.celrep.2015.08.002.

  4. An H, Cha KM, Choi SY, Shin HC. Data compression of excitatory postsynaptic potentials. Electronics Lett. 2015 Aug 31; 51(18):1407-1409. doi: 10.1049/el.2015.1133.

  5. Yu J, Park MH, Choi SY*, Jo SH*. Cortisone and hydrocortisone inhibit human Kv1.3 activity in a non-genomic manner. Naunyn Schmiedebergs Arch Pharmacol. 2015 June; 388(6):653-661. doi:10.1007/s00210-015-1109-2. 

  6. Lee K, Choi S, Choi LM, Lee J, Kim JH, Chung G, Lee G, Choi SY*, Park K. Desipramine inhibits salivary Ca2+ signaling and aquaporin translocation. Oral Dis. 2015 May;21(4):530-535. doi: 10.1111/odi.12317. 

  7. Park SJ, Lee JY, Kim SJ, Choi SY, Yune TY, Ryu JH. Tolllike receptor2 deficiency induces schizophrenialike behaviors in mice. Sci Rep. 2015 Feb 17;5:8502. doi: 10.1038/srep08502.

  8. Park H, Han KS, Seo J, Lee J, Dravid SM, Woo J, Chun H, Cho S, Bae JY, An H, Koh W, Yoon BE, Berlinguer-Palmini RB, Mannaioni G, Traynelis SF, Bae YC, Choi SY*, Lee CJ*. Channelmediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors. Mol Brain. 2015 Feb 3;8(1):7. doi: 10.1186/s13041-015-0097-y.

  9. Shin YH, Jin M, Hwang SM, Choi S, Namkoong E, Kim MK, Park MY, Choi SY, Lee JH, Park K. Epigenetic modulation of the muscarinic type 3 receptor in salivary epithelial cells. Lab Invest. 2015 Feb;95(2):237-45. doi: 10.1038/labinvest.2014.150. 

  10. Choi a, Jung S, Nah J, Ko HY, Jo SH, Chung G, Park K, Jung YK, Choi SY. Low levels of methyl beta-cyclodextrin disrupt GluA1-dependent synaptic potentiation but not for synaptic depression. J Neurochem. 2015 Feb;132(3):276-85. doi: 10.1111/jnc.12995.

  11. Lee K, Kim SJ, Kim D, Jo SH, Lee SJ, Choi SY. Prostaglandin modulates TLR3induced cytokine expression in human astroglioma cells. Brain Res. 2014 Nov 17; 1589(1):54-60. DOI: 10.1016/j.brainres.2014.06.036.

  12. Wang SHJ, Celic I, Choi SY, Wang Q, Sun LO, Vasioukhin V, Huganir RL, Kolodkin AL. Dlg5 Regulates Dendritic Spine Formation and Synaptogenesis by Controlling Subcellular Localization of N-cadherin. J Neurosci. 2014 Sep 17;34(38):12745-61. doi: 10.1523/JNEUROSCI.1280-14.2014.

  13. Hwang H, Min H, Kim D, Yu SW, Jung SJ, Choi SY*, Lee SJ*. Imiquimod induces a Toll-like receptor 7-independent increase in intracellular calcium via IP3 receptor activation. Biochem Biophys Res Commun. 2014 Jul 18;450(1):875879. doi: 10.1016/j.bbrc.2014.06.084.

  14. Choi TY, Kwon JE, Durrance ES, Jo SH, Choi SY*, Kim KT*. Melatonin inhibits voltagesensitive Ca2+ channelmediated neurotransmitter secretion. Brain Res. 2014 Apr 4;1557(1):34-42. doi: 10.1016/j.brainres.2014.02.023.

  15. Sharma K, Choi SY, Zhang Y, Nieland T, Long S, Li M, Huganir R. High-throughput genetic screen for synaptogenic factors: Identification of LRP6 as critical for excitatory synapse development. Cell Rep. 2013 Dec 12;5(5):1330-1341. doi: 10.1016/j.celrep.2013.11.008.

  16. Anggono V, KoçSchmitz Y, Widagdo J, Kormann J, Quan A, Chen CM, Robinson PJ, Choi SY, Linden DJ, Plomann M, Huganir RL. PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar longterm depression. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13976-81. doi: 10.1073/pnas.1312467110. Epub 2013 Aug 5.

  17. Kam TI, Song S, Gwon Y, Park H, Yan JJ, Im I, Choi JW, Choi TY, Kim J, Song DK, Takai T, Kim YC, Kim KS, Choi SY, Choi S, Klein WL, Yuan J, Jung YK. FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease. J Clin Invest. 2013 Jul 1;123(7):2791-802. doi: 10.1172/JCI66827.

  18. Tran TM, Park MY, Lee J, Bae JS, Hwang SM, Choi SY, Mikoshiba K, Park K. IRBIT plays an important role in NHE3mediated pHi regulation in HSG cells. Biochem Biophys Res Commun. 2013 Jul 19;437(1):1822. doi: 10.1016/j.bbrc.2013.06.010. 

  19. Shin YH, Namkoong E, Choi S, Bae JS, Jin M, Hwang SM, Arote R, Choi SY, Park K. Capsaicin regulates the NFκB pathway in salivary gland inflammation. J Dent Res. 2013 Jun;92(6):547-52. doi: 10.1177/0022034513487376. 

  20. Dolan BM, Duron SG, Campbell DA, Vollrath B, Shankaranarayana Rao BS, Ko HY, Lin GG, Govindarajan A, Choi SY, Tonegawa S. Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the smallmolecule PAK inhibitor FRAX486. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5671-6. doi: 10.1073/pnas.1219383110. 

  21. Sim HR, Choi TY, Lee HJ, Kang EY, Yoon S, Han PL, Choi SY*, Baik JH*. Role of dopamine D2 receptors in plasticity of stressinduced addictive behaviours. Nat Commun. 2013;4:1579. doi: 10.1038/ncomms2598.

  22. Seo J, Hong J, Lee SJ, Choi SY. cJun Nterminal phosphorylation is essential for hippocampal synaptic plasticity. Neurosci Lett. 2012 Nov 30;531(1):14-9. doi: 10.1016/j.neulet.2012.09.048.

  23. Kang JA, Lee K, Lee KM, Cho S, Seo J, Hur EM, Park CS, Baik JH, Choi SY. Desipramine inhibits histamine H1 receptor-induced Ca2+ signaling in rat hypothalamic cells. PLOS ONE. 2012;7(4):e36185. doi: 10.1371/journal.pone.0036185. 

  24. Jin M, Hwang SM, Koo NY, Kim B, Kho HS, Choi SY, Song YW, Park K. Autoantibodies in Sjögren's syndrome patients acutely inhibit muscarinic receptor function. Oral Dis. 2012 Mar;18(2):132-9. doi: 10.1111/j.1601-0825.2011.01853.x. 

  25. Seo J, Kim K, Jang S, Han S, Choi SY*, Kim E*. Regulation of hippocampal long-term potentiation and long-term depression by diacylglycerol kinase ζ. Hippocampus. 2012 May;22(5):1018-26. doi: 10.1002/hipo.20889. 

  26. Won H, Mah W, Kim E, Kim JW, Hahm EK, Kim MH, Cho S, Kim J, Jang H, Cho SC, Kim BN, Shin MS, Seo J, Jeong J, Choi SY, Kim D, Kang C, Kim E. GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice. Nat Med. 2011 May;17(5):566-72. doi: 10.1038/nm.2330.

  27. Hwang SM, Koo NY, Jin M, Davies AJ, Chun GS, Choi SY, Kim JS, Park K. Intracellular acidification is associated with changes in free cytosolic calcium and inhibition of action potentials in rat trigeminal ganglion. J Biol Chem. 2011 Jan 21;286(3):171929. doi: 10.1074/jbc.M109.090951. 

  28. Yang J, Seo J, Nair R, Han S, Jang S, Kim K, Han K, Paik SK, Choi J, Lee S, Bae YC, Topham MK, Prescott SM, Rhee JS, Choi SY*, Kim E*. DGKι regulates presynaptic release during mGluRdependent LTD. EMBO J. 2011 Jan 5;30(1):16580. doi: 10.1038/emboj.2010.286. Epub 2010 Nov 30.

2005-2010

  1. Hong J, Cho IH, Kwak KI, Suh EC, Seo J, Min HJ, Choi SY, Kim CH, Park SH, Jo EK, Lee S, Lee KE, Lee SJ. Microglial Tolllike receptor 2 contributes to kainic acidinduced glial activation and hippocampal neuronal cell death. J Biol Chem. 2010 Dec 10;285(50):3944757. doi: 10.1074/jbc.M110.132522.

  2. Han S, Nam J, Li Y, Kim S, Cho SH, Cho YS, Choi SY, Choi J, Han K, Kim Y, Na M, Kim H, Bae YC, Choi SY, Kim E. Regulation of dendritic spines, spatial memory, and embryonic development by the TANC family of PSD-95-interacting proteins. J Neurosci. 2010 Nov 10;30(45):15102-12 doi: 10.1523/JNEUROSCI.3128-10.2010.

  3. Oh D, Han S, Seo J, Lee JR, Choi J, Groffen J, Kim K, Cho YS, Choi HS, Shin H, Woo J, Won H, Park SK, Kim SY, Jo J, Whitcomb DJ, Cho K, Kim H, Bae YC, Heisterkamp N, Choi SY*, Kim E*. Regulation of synaptic Rac1 activity, longterm potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins. J Neurosci. 2010 Oct 20;30(42):14134-44. doi: 10.1523/JNEUROSCI.1711-10.2010.

  4. Seo J, Koo NY, Choi WY, Kang JA, Min JH, Jo SH, Lee SJ, Oh SB, Kim JS, Lee JH, Choi SY*, Park K. Sphingosine1phosphate signaling in human submandibular cells. J Dent Res. 2010 Oct;89(10):1148-53. doi: 10.1177/0022034510376044. 

  5. Kim KS, Yoon YR, Lee HJ, Yoon S, Kim SY, Shin SW, An JJ, Kim MS, Choi SY, Sun W, Baik JH. Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors. J Biol Chem. 2010 Mar 19;285(12):8905-17. doi: 10.1074/jbc.M109.079590. 

  6. Yoon S, Noh JS, Choi SY, Baik JH. Effects of atypical antipsychotic drugs on body weight and food intake in dopamine D2 receptor knockout mice. Biochem Biophys Res Commun. 2010 Mar 5;393(2):235-41. doi: 10.1016/j.bbrc.2010.01.108.

  7. Kim D, Cho SH, Kim JS, Jo SH, Lee SJ, Kim KT, Choi SY. Human astrocytic bradykinin B(2) receptor modulates zymosan-induced cytokine expression in 1321N1 cells. Peptides. 2010 Jan;31(1):101-7. doi: 10.1016/j.peptides.2009.10.011.

  8. Han K, Kim MH, Seeburg D, Seo J, Verpelli C, Han S, Chung HS, Ko J, Lee HW, Kim K, Heo WD, Meyer T, Kim H, Sala C, Choi SY, Sheng M, Kim E. Regulated RalBP1 binding to RalA and PSD95 controls AMPA receptor endocytosis and LTD. PLoS Biol. 2009 Sep;7(9):e1000187. doi: 10.1371/journal.pbio.1000187. 

  9. Kim K, Yang J, Zhong XP, Kim MH, Kim YS, Lee HW, Han S, Choi J, Han K, Seo J, Prescott SM, Topham MK, Bae YC, Koretzky G, Choi SY, Kim E. Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. EMBO J. 2009 Apr 22;28(8):1170-9. doi: 10.1038/emboj.2009.44.

  10. Kim MH, Choi J, Yang J, Chung W, Kim JH, Paik SK, Kim K, Han S, Won H, Bae YS, Cho SH, Seo J, Bae YC, Choi SY, Kim E. Enhanced NMDA receptor-mediated synaptic transmission, enhanced long-term potentiation, and impaired learning and memory in mice lacking IRSp53. J Neurosci. 2009 Feb 4;29(5):1586-95. doi: 10.1523/JNEUROSCI.4306-08.2009. 

  11. Kim WR, Park OH, Choi S, Choi SY, Park SK, Lee KJ, Rhyu IJ, Kim H, Lee YK, Kim HT, Oppenheim RW, Sun W. The maintenance of specific aspects of neuronal function and behavior is dependent on programmed cell death of adult-generated neurons in the dentate gyrus. Eur J Neurosci. 2009 Apr;29(7):1408-21. doi: 10.1111/j.1460-9568.2009.06693.x.

  12. Hwang SM, Li J, Koo NY, Choi SY, Lee SJ, Oh SB, Castro R, Kim JS, Park K. Role of purinergic receptor in alpha fodrin degradation in Par C5 cells. J Dent Res. 2009 Oct;88(10):927-32. doi: 10.1177/0022034509342227.

  13. Kim JH, Park SH, Moon YW, Hwang S, Kim D, Jo SH, Oh SB, Kim JS, Jahng JW, Lee JH, Lee SJ, Choi SY*, Park K. Histamine H1 receptor induces cytosolic calcium increase and aquaporin translocation in human salivary gland cells. J Pharmacol Exp Ther. 2009 Aug;330(2):403-12doi: 10.1124/jpet.109.153023.

  14. Koo NY, Li J, Hwang SM, Choi SY, Lee SJ, Oh SB, Kim JS, Lee EB, Song YW, Park K. Functional epitope of muscarinic type 3 receptor which interacts with autoantibodies from Sjogren's syndrome patients. Rheumatology (Oxford). 2008 Jun;47(6):828-33doi: 10.1093/rheumatology/ken064. Epub 2008 Apr 9.

  15. Park C, Cho IH, Kim D, Jo EK, Choi SY, Oh SB, Park K, Kim JS, Lee SJ. Tolllike receptor 2 contributes to glial cell activation and heme oxygenase-1 expression in traumatic brain injury. Neurosci Lett. 2008 Jan 31;431(2):123-8. doi: 10.1016/j.neulet.2007.11.057.

  16. Li HY, Park CK, Jung SJ, Choi SY, Lee SJ, Park K, Kim JS, Oh SB. Eugenol inhibits K+ currents in trigeminal ganglion neurons. J Dent Res. 2007 Sep;86(9):898-902.

  17. Hayashi ML, Rao BS, Seo J, Choi HS, Dolan BM, Choi SY, Chattarji S, Tonegawa S. Inhibition of p21activated kinase rescues symptoms of fragile X syndrome in mice. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11489-94. 

  18. Lee H, Park C, Cho IH, Kim HY, Jo EK, Lee S, Kho HS, Choi SY, Oh SB, Park K, Kim JS, Lee SJ. Doublestranded RNA induces iNOS gene expression in Schwann cells, sensory neuronal death, and peripheral nerve demyelination. Glia. 2007 May;55(7):712-22.

  19. Kim D, Kim MA, Cho IH, Kim MS, Lee S, Jo EK, Choi SY, Park K, Kim JS, Akira S, Na HS, Oh SB, Lee SJ. A Critical Role of Tolllike Receptor 2 in Nerve Injury-induced Spinal Cord Glial Cell Activation and Pain Hypersensitivity. J Biol Chem. 2007 May 18;282(20):14975-83. 

  20. Kim DC, Choi SY, Kim SH, Yun BS, Yoo ID, Reddy NR, Yoon HS, Kim KT. Isoliquiritigenin selectively inhibits H2 histamine receptor signaling. Mol Pharmacol. 2006 Aug;70(2):493-500. 

  21. Park CK, Li HY, Yeon KY, Jung SJ, Choi SY, Lee SJ, Lee S, Park K, Kim JS, Oh SB. Eugenol inhibits sodium currents in dental afferent neurons. J Dent Res. 2006 Oct;85(10):900-4.

  22. Li J, Lee S, Choi SY, Lee SJ, Oh SB, Lee JH, Chung SC, Kim JS, Lee JH, Park K. Effects of pilocarpine on the secretory acinar cells in human submandibular glands. Life Sci. 2006 Nov 25;79(26):2441-7. 

  23. Li J, Koo NY, Cho IH, Kwon TH, Choi SY, Lee SJ, Oh SB, Kim JS, Park K. Expression of sodium bicarbonate cotransporter and its role in pHi regulation in guinea pig salivary glands. Am J Physiol Gastrointest Liver Physiol. 2006 Dec;291(6):G1031-40.

  24. Lee H, Jo EK, Choi SY, Oh SB, Park K, Kim JS, Lee SJ. Necurotic neuronal cells induce inflammatory Schwann cell activation via TLR2 and TLR3 : implication in Wallerinal degeneration. Biochem Biophys Res Commun. 2006 Nov 24;350(3):742-7. 

  25. Choi SY, Li J, Jo SH, Lee SJ, Oh SB, Kim JS, Lee JH, Park K. Desipramine Inhibits Na+/H+ Exchanger in Human Submandibular Cells. J Dent Res. 2006 Sep;85(9):839-43.

  26. Ahn KJ, Jeong HK, Choi HS, Ryoo SR, Kim YJ, Goo JS, Choi SY, Han JS, Ha IH, Song WJ. DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects. Neurobiol Dis. 2006 Jun;22(3):463-72. 

  27. Park CK, Kim MS, Fang Z, Li HY, Jung SJ, Choi SY, Lee SJ, Park K, Kim JS, Oh SB. Functional expression of thermo-transient receptor potential channels in dental primary afferent neurons: Implication for tooth pain. J Biol Chem. 2006 Jun 23;281(25):17304-11. 

  28. Piao L, Ying Li H, Park CK, Cho IH, Piao ZG, Jung SJ, Choi SY, Lee SJ, Park K, Kim JS, Oh SB. Mechanosensitivity of voltage-gated K+ currents in rat trigeminal ganglion neurons. J Neurosci Res. 2006 May 15;83(7):1373-80.

  29. Piao ZG, Cho IH, Park CK, Hong JP, Choi SY, Lee SJ, Lee S, Park K, Kim JS, Oh SB. Activation of glia and microglial p38 MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury. Pain. 2006 Apr;121(3):219-31. 

  30. Koo NY, Li J, Hwang SM, Choi SY, Lee SJ, Oh SB, Kim JS, Lee JH, Park K. Molecular cloning and functional expression of a sodium bicarbonate cotransporter from guinea-pig parotid glands. Biochem Biophys Res Commun. 2006 Apr 21;342(4):1114-22. 

  31. Cho IH, Chung YM, Park CK, Park SH, Li HY, Kim D, Piao ZG, Choi SY, Lee SJ, Park K, Kim JS, Jung SJ, Oh SB. Systemic administration of minocycline inhibits formalin-induced inflammatory pain in rat. Brain Res. 2006 Feb 9;1072(1):208-14. 

  32. Kim MS, Park CK, Yeon KY, Li HY, Jung SJ, Choi SY, Lee SJ, Park K, Kim JS, Oh SB. Involvement of transient receptor potential vanilloid-1 in calcium current inhibition by capsaicin. Neuroreport. 2006 Feb 6;17(2):145-9.

  33. Park C, Lee S, Cho IH, Lee HK, Kim D, Choi SY, Oh SB, Park K, Kim JS, Lee SJ. TLR3-mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: Differential signaling mechanisms of TLR3-induced IP-10 and IL-8 gene expression. Glia. 2006 Feb;53(3):248-56.

  34. Choi SY, Chang J, Jiang B, Seol GH, Min SS, Han JS, Shin HS, Gallagher M, Kirkwood A. Multiple receptors coupled to phospholipase C gate long-term depression in visual cortex. J Neurosci. 2005 Dec 7;25(49):11433-43.

서울대학교 치의학대학원 시냅스네트워크연구실 / Tel : 02-740-8650  Fax : 02-765-5107  E-mail : sychoi@snu.ac.kr

Synaptic Network Laboratory, Seoul National University

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